(Rac)-Nebivolol-d4 (hydrochloride), CAS 2701283-32-9

(Rac)-Nebivolol-d4 (hydrochloride), CAS 2701283-32-9
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MEXHY-W752055-0
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MedChemExpress

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Product Description: (Rac)-Nebivolol-d4 hydrochloride is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1-adrenergic receptor with an IC50 of 0.8 nM[1][2][3].

Formula: C22H22D4ClF2NO4

References: [1]Mercanoglu G, et al. The effects of nebivolol on apoptosis in a rat infarct model. Circ J. 2008 Apr;72(4):660-70./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[3]Brehm BR, et al. Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells. Cardiovasc Res. 2001 Feb 1;49(2):430-9.

CAS Number: 2701283-32-9

Molecular Weight: 445.92

Research Area: Endocrinology; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Adrenergic Receptor
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SKU MEXHY-W752055-0
Manufacturer MedChemExpress
Manufacturer SKU HY-W752055-0
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