Product Description: Ramiprilat-d4 hydrochloride is deuterated labeled Ramiprilat (HY-A0115). Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1].
Applications: Neuroscience-Neuromodulation
Formula: C21H25D4ClN2O5
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active <b>angiotensin converting enzyme (ACE)</b> inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research<sup>[1]</sup>.
Molecular Weight: 428.94
Research Area: Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Angiotensin-converting Enzyme (ACE);Drug Metabolite;Endogenous Metabolite;Isotope-Labeled Compounds