Succinic anhydride-d4, CAS 14341-86-7

Product Description: Succinic anhydride-d4 is the deuterium labeled Succinic anhydride. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[1].

Formula: C4D4O3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Dale Boger.et al. Chimer containing a targeting portion linked to a scission-activated duocarmycin-type prodrug. WO2009064913A1.

CAS Number: 14341-86-7

Molecular Weight: 104.10

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;Isotope-Labeled Compounds

• SKU: MEXHY-79369S-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-79369S-100
• Package Unit: 100 mg
• Quantity Unit: STK