Sulindac sulfide-d3, CAS 250608-66-3

Product Description: Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.

Applications: Neuroscience-Neurodegeneration

Formula: C20H14D3FO2S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Takahashi Y, et al. Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation. J Biol Chem. 2003 May 16;278(20):18664-70.

CAS Number: 250608-66-3

Molecular Weight: 343.43

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;γ-secretase

• SKU: MEXHY-B1786S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B1786S-5
• Green Labware: No
• Package Unit: 5mg
• Quantity Unit: STK