Tauro-α-muricholic acid-d4-1 (sodium)

Product Description: Tauro-α-muricholic acid-d4-1 (sodium) is deuterium labeled Tauro-α-muricholic acid (sodium). Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR (Farnesoid X receptor) antagonist (IC50=28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal[1][2][3].

Formula: C26H40D4NNaO7S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Chen W, et al. Farnesoid X receptor is inhibited after ileum transposition in diabetic rats: its hypoglycemic effect. Int J Med Sci. 2023 Apr 2;20(5):595-605./[3]Ye X, et al. Sodium butyrate alleviates cholesterol gallstones by regulating bile acid metabolism. Eur J Pharmacol. 2021 Oct 5;908:174341.

Molecular Weight: 541.71

Research Area: Others

Target: Endogenous Metabolite;FXR;Isotope-Labeled Compounds

• SKU: MEXHY-W654353-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W654353-0
• Package Unit: Get quote
• Quantity Unit: STK