Product Description: Temephos-d12 is the deuterium labeled Temephos[1]. Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae. Temefos affects the central nervous system through inhibition of cholinesterase, results in death before reaching the adult stage[2][3].
Applications: COVID-19-immunoregulation
Formula: C16H8D12O6P2S3
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Thirugnanam M, et al. Environmental impact of mosquito pesticides: influence of temefos on the brain acetylcholinesterase of killifish. Environ Physiol Biochem. 1975;5(6):451-9./[3]Wirth MC, et al. Selection and characterization of temephos resistance in a population of Aedes aegypti from Tortola, British Virgin Islands. J Am Mosq Control Assoc. 1999 Sep15(3):315-20.
CAS Number: 1219795-39-7
Molecular Weight: 478.54
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Parasite
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