Product Description: Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria)[1][2].
Applications: COVID-19-immunoregulation
Formula: C12H12D3Cl2NO5S
References: [1]A Marchese, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61./[2]Marta Tikhomirov, et al. Pharmacokinetics of florfenicol and thiamphenicol in ducks. J Vet Pharmacol Ther. 2019 Jan;42(1):116-120.
CAS Number: 2211914-19-9
Molecular Weight: 359.24
Compound Purity: 98.0
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Antibiotic;Bacterial;Isotope-Labeled Compounds
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