Thymine-13C5,15N2, CAS 2483830-13-1

Product Description: Thymine-13C5,15N2 (5-Methyluacil-13C5,15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[1].

Formula: 13C5H6 15N2O2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6.

CAS Number: 2483830-13-1

Molecular Weight: 133.06

Research Area: Cancer;Metabolic Disease

Target: Endogenous Metabolite;Isotope-Labeled Compounds

• SKU: MEXHY-W010450S5-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W010450S5-0
• Package Unit: Get quote
• Quantity Unit: STK