trans-Isoferulic acid-d3, CAS 1028203-97-5

Product Description: trans-Isoferulic acid-d3 is the deuterium labeled trans-Isoferulic acid[1]. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity[2].trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)[3].

Applications: COVID-19-immunoregulation

Formula: C10H7D3O4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Kai-Hui Sun, et al. A new indole-type alkaloid from the roots of <i>Clematis florida var. plena</i>. Nat Prod Res. 2019 Oct;33(20):2925-2931./[3]Matharage Gayani Dilshara, et al. Downregulation of NO and PGE2 in LPS-stimulated BV2 microglial cells by trans-isoferulic acid via suppression of PI3K/Akt-dependent NF-κB and activation of Nrf2-mediated HO-1. Int Immunopharmacol. 2014 Jan18(1):203-11.

CAS Number: 1028203-97-5

Molecular Weight: 197.20

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: NO Synthase;Prostaglandin Receptor

• SKU: MEXHY-N0761AS-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N0761AS-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK