Product Description: Tricaine-d5 (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used anaesthetic agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used anaesthetic in fish, has been shown to induce embryotoxic effects in zebrafish[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C10H10D5NO5S
References: [1]Félix LM, et al. Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222. Toxicol Appl Pharmacol. 2021;412:115385. /[2]Félix LM, et al. MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos. Comp Biochem Physiol C Toxicol Pharmacol. 2020;237:108834.
Molecular Weight: 266.33
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds
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