Product Description: Urea-13C,15N2 is the 13C and 15N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
Formula: 13CH4 15N2O
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7./[3]Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 1519(11):20392.Wang H, et al. Urea. Subcell Biochem. 201473:7-29./[4]Wang H, et al. Urea. Subcell Biochem. 201473:7-29.
CAS Number: 58069-83-3
Molecular Weight: 63.03
Compound Purity: 99.10
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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