Product Description: Urea-15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
Formula: CH4 15N2O
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7./[3]Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 15;19(11):20392./[4]Wang H, et al. Urea. Subcell Biochem. 2014;73:7-29.
CAS Number: 2067-80-3
Molecular Weight: 62.04
Compound Purity: 98.0
Research Area: Cardiovascular Disease; Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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