Vismodegib-d7, CAS 2733145-73-6

Product Description: Vismodegib-d7 is deuterium labeled Vismodegib. Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively[1][2].

Formula: C19H7D7Cl2N2O3S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

CAS Number: 2733145-73-6

Molecular Weight: 428.34

Research Area: Cancer

Target: Isotope-Labeled Compounds

• SKU: MEXHY-W716916-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W716916-0
• Package Unit: Get quote
• Quantity Unit: STK