Xylometazoline-d4 (hydrochloride)

Xylometazoline-d4 (hydrochloride)
SKU
MEXHY-B0475S-0
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MedChemExpress

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Product Description: Xylometazoline-d4 hydrochloride is deuterated labeled Xylometazoline hydrochloride (HY-B0475). Xylometazoline hydrochloride is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research[1][2].

Applications: COVID-19-immunoregulation

Formula: C16H21D4ClN2

References: [1]Ronald Eccles, et al. The nasal decongestant effect of xylometazoline in the common cold. Am J Rhinol. 2008 Sep-Oct;22(5):491-6./[2]Britta Haenisch, et al. Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline. Fundam Clin Pharmacol. 2010 Dec;24(6):729-39./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 284.86

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Adrenergic Receptor;Isotope-Labeled Compounds
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SKU MEXHY-B0475S-0
Manufacturer MedChemExpress
Manufacturer SKU HY-B0475S-0
Green Labware No
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