Product Description: 2-Deoxy-2-sulfoamino-D-glucose sodium (D-Glucosamine-2-N-sulfate sodium) is an endogenous metabolite. The main regulatory mechanism of 2-Deoxy-2-sulfoamino-D-glucose sodium involves the interaction of sulfuric acid groups with biomolecules. Sulfate groups can influence the charge density and configuration of polysaccharides, thereby regulating their ability to bind to proteins such as antithrombin. This combination can enhance the activity of antithrombin, which in turn inhibits key enzymes in the blood clotting process to achieve anti-clotting effects. 2-Deoxy-2-sulfoamino-D-glucose sodium can be used to study the selective removal of n-sulfate groups from Heparin (HY-17567) which has important implications for understanding the biological activity of heparin and developing related drugs[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C6H12NNaO8S
References: [1]Nagasawa K, et al. Solvolytic desulfation of 2-deoxy-2-sulfoamino-D-glucose and D-glucose 6-sulfate[J]. Carbohydrate Research, 1974, 36(2): 265-271.
CAS Number: 38899-05-7
Molecular Weight: 281.22
Research Area: Metabolic Disease
Solubility: H2O : 125 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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