2-Ketoglutaric acid (potassium), CAS 997-43-3

Product Description: 2-Ketoglutaric acid potassium (Alpha-Ketoglutaric acid potassium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid potassium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid potassium is a reversible inhibitor of tyrosinase with an IC50 value of 15 mM[1][2].

Formula: C5H6KO5

References: [1]Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35. /[2]Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662.

CAS Number: 997-43-3

Molecular Weight: 185.20

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Tyrosinase

• SKU: MEXHY-W013636C-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W013636C-0
• Package Unit: Get quote
• Quantity Unit: STK