Product Description: Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor[1][2][3].
Applications: COVID-19-anti-virus
Formula: NH4Cl
References: [1]Yu C,et al. Lysosome dysfunction enhances oxidative stress-induced apoptosis through ubiquitinated protein accumulation in Hela cells. Anat Rec (Hoboken). 2013 Jan;296(1):31-9. /[2]Huang X, et al. NH4Cl treatment prevents doxorubicin-induced myocardial dysfunction in vivo. Life Sci. 2019;227:94-100. /[3]Canning WM, Fields BN. Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells. Science. 1983;219(4587):987-988.
CAS Number: 12125-02-9
Molecular Weight: 53.49
Compound Purity: 99.5
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)
Target: Autophagy
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