Product Description: AMP-PNP lithium hydrate is a non-hydrolyzable analog of ATP. AMP-PNP can replace ATP for biological research and is not hydrolyzed by intracellular enzymes. In the study of BtuCD-F, a vitamin B12 transporter, it was found that AMP-PNP can block the channel formed by the two BtuCDs of the BtuCD-F complex, thereby preventing the entry of vitamin B12[1].
Formula: C10H17N6O12P3.xLi.yH2O
References: [1]Korkhov VM, et al. Structure of AMP-PNP-bound vitamin B12 transporter BtuCD-F. Nature. 2012 Oct 18;490(7420):367-72.
Molecular Weight: N/A
Compound Purity: 94.0
Research Area: Metabolic Disease
Solubility: H2O : 50 mg/mL (ultrasonic;warming)
Target: Others