Product Description: BAPTA-AM is a well-known membrane permeable Ca2+ chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively[1].
Formula: C34H40N2O18
References: [1]Tang Q, et al. The membrane permeable calcium chelator BAPTA-AM directly blocks human ether a-go-go-related gene potassium channels stably expressed in HEK 293 cells. Biochem Pharmacol. 2007 Dec 3;74(11):1596-607./[2]Wie MB, et al. BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures. Prog Neuropsychopharmacol Biol Psychiatry. 2001 Nov;25(8):1641-59.
CAS Number: 126150-97-8
Molecular Weight: 764.68
Compound Purity: 99.80
Research Area: Cardiovascular Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : 1 mg/mL (ultrasonic)
Target: Potassium Channel
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