Product Description: Benzamidine (Benzenecarboximidamide) hydrochloride hydrate is a reversible competitive trypsin-like serine proteases inhibitor with Kis of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively[1][2].
Applications: Cancer-Kinase/protease
Formula: C7H8N2.ClH.xH2O
References: [1]Katz BA, et al. Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator. Chem Biol. 2000 Apr;7(4):299-312./[2]J A Cairns, et al. Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts. J Clin Invest. 1997 Mar 15;99(6):1313-21.
CAS Number: 206752-36-5
Molecular Weight: N/A
Compound Purity: 99.96
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Ser/Thr Protease
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