Caspase-4 Inhibitor Screening Assay Kit

Shelf life (days): 365

Notes: Cayman’s Caspase-4 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human caspase-4, a major upstream effector of non-canonical inflammasome activation. The assay uses a caspase-4-specific fluorogenic substrate, Ac-LEVD-AFC. Caspase-4 cleaves this substrate generating free AFC, which can be easily quantified using a fluorescence plate reader at excitation and emission wavelengths of 400 and 505 nm, respectively. The potent and reversible caspase-4 inhibitor AC-LEVD-CHO is included as a positive control.

• SKU: CAY701820
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 701820-384
• Green Labware: No
• Package Unit: 384 wells
• Quantity Unit: PAK
• Application: Fluorescence