Caspase-6 Inhibitor Screening Assay Kit

Shelf life (days): 365

Notes: Cayman’s Caspase-6 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human caspase-6, a cysteine protease implicated in multiple neurodegenerative disorders. The assay uses a caspase-6-specific fluorogenic substrate, Z-VEID-AFC. Caspase-6 cleaves this substrate generating free AFC, which can be easily quantified using a fluorescence plate reader at excitation and emission wavelengths of 400 and 505 nm, respectively. The potent and reversible caspase-6 inhibitor Ac-VEID-CHO is included as a positive control and inhibits caspase-6 with an IC50 value of 12 nM.

• SKU: CAY701890
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 701890-384
• Green Labware: No
• Package Unit: 384 wells
• Quantity Unit: PAK