Product Description: Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na+ transport produced by Alloxan[1][2]. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models[3].
Applications: Neuroscience-Neuromodulation
Formula: ClCs
References: [1]Sun J, Shen W, et al. A Chinese Medicine Formula "Xian-Jia-Tang" for Treating Bladder Outlet Obstruction by Improving Urodynamics and Inhibiting Oxidative Stress through Potassium Channels. Evid Based Complement Alternat Med. 2017;2017:8147258./[2]Soto C, et al. Alloxan decreases intracellular potassium content of the isolated frog skin epithelium. Comp Biochem Physiol C Toxicol Pharmacol. 2001;130(1):19-27./[3]Ouyang JS, Li YP, Li CY, et al. Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. Free Radic Res. 2012;46(12):1437-1445./[4]O'Brien CE, et al. Cesium-induced QT-interval prolongation in an adolescent. Pharmacotherapy. 2008;28(8):1059-1065.
CAS Number: 7647-17-8
Molecular Weight: 168.36
Compound Purity: 99.93
Research Area: Cardiovascular Disease
Solubility: H2O : ≥ 100 mg/mL
Target: Potassium Channel