Product Description: Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice[1][2][3].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C6H10O8
References: [1]Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar;66(2):275-82./[2]Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan;90(1):38-44. /[3]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct;33(10):4411-20.
CAS Number: 5949-29-1
Molecular Weight: 210.14
Compound Purity: 98.0
Research Area: Metabolic Disease; Inflammation/Immunology
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Antibiotic;Apoptosis;Endogenous Metabolite
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