Product Description: Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C6H5Na3O7
Citations: Insect Biochem Mol Biol. 2023 May 12;103958./Food Chem. 2022: 134807./New J Chem. 03 Aug 2022.
References: [1]Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar;66(2):275-82./[2]Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan;90(1):38-44./[3]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct;33(10):4411-20.
CAS Number: 68-04-2
Molecular Weight: 258.07
Compound Purity: 98.0
Research Area: Metabolic Disease
Solubility: H2O : 50 mg/mL (ultrasonic)
Target: Apoptosis;Endogenous Metabolite
English
Deutsch
