Product Description: Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells[1].
Formula: C8H12O4
References: [1]Andrea Gille, et al. Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate. Redox Biol. 2019 Jan;20:19-27.
CAS Number: 141-05-9
Molecular Weight: 172.18
Compound Purity: 99.30
Research Area: Others
Solubility: DMSO : 100 mg/mL (ultrasonic)/Ethanol : ≥ 100 mg/mL
Target: Biochemical Assay Reagents