Product Description: Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues. Diethyl pyrocarbonate can be used for modeling[1].
Formula: C6H10O5
References: [1]E E Nattie. Diethyl pyrocarbonate (an imidazole binding substance) inhibits rostral VLM CO2 sensitivity. J Appl Physiol (1985). 1986 Sep;61(3):843-50./[2]Uzvölgyi E, et al. In vivo formation of a carcinogenic substance from diethyl pyrocarbonate in the presence of ammonia. Arch Toxicol Suppl. 1985;8:490-3.
CAS Number: 1609-47-8
Molecular Weight: 162.14
Compound Purity: 99.66
Research Area: Neurological Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : ≥ 33.33 mg/mL
Target: Biochemical Assay Reagents
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