Product Description: DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research[1][2][3].
Applications: Cancer-programmed cell death
Formula: (C2H4O)nC63H104N9O15P.2H3N
References: [1]Werner ME, et, al. Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis. Biomaterials. 2011 Nov;32(33):8548-54./[2]Li Y, et, al. Self-Assembled Nanoparticles Based on Amphiphilic Anticancer Drug-Phospholipid Complex for Targeted Drug Delivery and Intracellular Dual-Controlled Release. ACS Appl Mater Interfaces. 2015 Aug 19;7(32):17573-81./[3]Patlolla RR, et al. Folate-targeted etoposide-encapsulated lipid nanospheres. J Drug Target. 2008 May;16(4):269-75.
CAS Number: 1236288-25-7
Molecular Weight: 3400.00
Compound Purity: 95.16
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Liposome
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