Product Description: Evans Blue (Direct Blue 53) is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue is a L-glutamate and kainate receptor-mediated currents inhibitor. Evans Blue has a strong affinity towards serum albumin, making it a high molecular weight protein tracer. Evans Blue is also used to study BBB (blood-brain barrier) permeability[1][2].
Formula: C34H24N6Na4O14S4
References: [1]Anatol Manaenko, et al. Comparison Evans Blue injection routes: Intravenous versus intraperitoneal, for measurement of blood-brain barrier in a mice hemorrhage model. J Neurosci Methods. 2011 Feb 15;195(2):206-10. /[2]Linpeng Yao, et al. Evans Blue Dye: A Revisit of Its Applications in Biomedicine. Contrast Media Mol Imaging. 2018 Apr 22:2018:7628037.
CAS Number: 314-13-6
Molecular Weight: 960.81
Compound Purity: 95.0
Research Area: Neurological Disease
Solubility: DMSO : ≥ 25 mg/mL/H2O : 33.33 mg/mL (ultrasonic)
Target: EAAT;iGluR
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