Formulation: A powder
Formal Name: (2R,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-(tetradecylamino)tetrahydro-2H-pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, trifluoroacetate salt
Purity: ≥90%
Formula Markup: C26H51NO10 • CF3COOH
Formula Weight: 651,7
Shelf life (days): 365
Notes: IMCTA-C14 is a detergent and derivative of the microbial metabolite 4-trehalosamine (Item No. 40229).{65892} It has a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. IMCTA-C14 (0.05 and 0.5%) extracts proteins, including membrane proteins, from OVK18 ovarian cancer cells. It is active against several strains of various bacteria (MICs = 8-128 µg/ml) and is cytotoxic against a panel of 52 cancer cell lines (IC50s = 2.9-29.2 µg/ml). IMCTA-C14 (50 µM) induces autophagy in OVK18 cells.