Product Description: N,N-Dimethylacetamide (DMAc) is an organic solvent with blood-brain transmissibility and an FDA-approved drug excipient. N, N-dimethylacetamide exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. N, N-dimethylacetamide can be used in studies of weight gain caused by a high-fat diet and neuroinflammation in Alzheimer's disease[1][2][3].
Formula: C4H9NO
References: [1]Sundaram S, et al. N,N-dimethylacetamide regulates the proinflammatory response associated with endotoxin and prevents preterm birth. Am J Pathol. 2013 Aug;183(2):422-30./[2]Wei ZH, et al. N,N-dimethylacetamide targets neuroinflammation in Alzheimer's disease in in-vitro and ex-vivo models. Sci Rep. 2023 May 1;13(1):7077./[3]Koya JB, et al. FDA-Approved Excipient N, N-Dimethylacetamide Attenuates Inflammatory Bowel Disease in In Vitro and In Vivo Models. Fortune J Health Sci. 2022;5:499-509.
CAS Number: 127-19-5
Molecular Weight: 87.12
Compound Purity: 99.98
Research Area: Metabolic Disease; Inflammation/Immunology; Neurological Disease
Solubility: DMSO : ≥ 100 mg/mL
Target: Biochemical Assay Reagents;NF-κB
English
Deutsch
