Product Description: NTPO trisodium is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO trisodium are abrogated by base excision repair (BER) but not nucleotide excision repair (NER)[1].
Applications: Cancer-programmed cell death
Formula: C3H9NNa3O9P3
References: [1]Choi JY, et al. Non-thermal plasma-induced apoptosis is modulated by ATR- and PARP1-mediated DNA damage responses and circadian clock. Oncotarget. 2016 May 31;7(22):32980-9.