Product Description: Protamine sulfate, polycationic peptide and a antiheparin agent, could neutralize the anticoagulant action of heparin and enhances lipid-mediated gene transfer[1][2][3].
Applications: Metabolism-sugar/lipid metabolism
Formula: N/A
References: [1]Li J, et al. Therapeutic effect of urine-derived stem cells for protamine/lipopolysaccharide-induced interstitial cystitis in a rat model. Stem Cell Res Ther. 2017 May 8;8(1):107./[2]Ahmed Kouta, et al. Protamine Sulfate Neutralization Profile of Various Dosages of Bovine, Ovine and Porcine UFHs and Their Depolymerized Derivatives in Non-Human Primates. Clin Appl Thromb Hemost. Jan-Dec 2021;27:10760296211005544./[3]F L Sorgi, et al. Protamine sulfate enhances lipid-mediated gene transfer. Gene Ther. 1997 Sep;4(9):961-8./[4]R J Cobel-Geard, et al. Interaction of protamine sulfate with thrombin. Am J Hematol. 1983 May;14(3):227-33./[5]Fionnuala Ni Ainle, et al. Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation. Blood. 2009 Aug 20;114(8):1658-65.
CAS Number: 9009-65-8
Molecular Weight: N/A
Compound Purity: 99.99
Research Area: Metabolic Disease
Solubility: H2O : ≥ 33.33 mg/mL
Target: Thrombin
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