Formulation: A crystalline solid
Formal Name: O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-D-glucose
Purity: ≥98%
Formula Markup: C25H43NO18
Formula Weight: 645,6
Shelf life (days): 1460
CAS Number: 56180-94-0
Notes: Acarbose is an oligosaccharide and inhibitor of α-glucosidases (IC50s = 0.16 and 2.9 µM for maltase and sucrase, respectively).{22628} It also activates phosphorylase kinase in a cell-free assay when used at a concentration of 250 µM.{31726} Acarbose (40 mg/kg in the diet) decreases urine levels of glucose and glycosylated hemoglobin, as well as glomerular mesangial thickening in a db/db mouse model of diabetic nephropathy.{63399} It reduces sucrose-induced increases in infarct size as a percentage of the area at risk and serum malondialdehyde (MDA) levels in a mouse model of cardiac ischemia-reperfusion injury induced by coronary artery ligation when administered at a dose of 10 mg/kg.{63400}
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