Formulation: A crystalline solid
Formal Name: D-fructose-1,2,3,4,5,6-13C6
Purity: ≥95%
Formula Markup: [13C]6H12O6
Formula Weight: 186,1
Shelf life (days): 1460
CAS Number: 201595-65-5
Notes: D-Fructose-13C6 is intended for use as an internal standard for the quantification of D-fructose by GC- or LC-MS. D-Fructose is a ubiquitous monosaccharide and is derived, in addition to glucose, from the breakdown of sucrose by sucrase in the intestine.{45964} It is a precursor in the biosynthesis of D-fructose-1,6-bisphosphate (Item No. 20516), which is an intermediate in the production of D-glucose via gluconeogenesis. Deficiencies in the enzymes that metabolize D-fructose are inborn errors of metabolism that range from benign, for fructokinase deficiency, to severe, for hereditary fructose intolerance, if D-fructose, sucrose, and sorbitol are not eliminated from the diet.{45965} Increased consumption of D-fructose is associated with obesity, dyslipidemia, and impaired insulin sensitivity.{45966}
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