Formulation: A solid
Formal Name: (3α,16α)-eburnamenin-14(15H)-one
Purity: ≥98%
Formula Markup: C19H22N2O
Formula Weight: 294,4
Shelf life (days): 1460
CAS Number: 4880-88-0
Notes: (−)-Eburnamonine is an indole alkaloid that has been found in K. jasminiflora and has vasodilator and neuroprotective activities.{65776,65777,65778} It increases cerebral blood flow and capillary circulation in anesthetized dogs when administered at a dose of 2.5 mg/kg.{65778} (−)-Eburnamonine (20 mg/kg) prevents scopolamine-induced amnesia in a passive avoidance test in mice.{65777} It enhances acquisition of the conditioned avoidance response induced by hypobaric hypoxia in rats when administered at a dose of 20 mg/kg. (−)-Eburnamonine (0.25 mg/kg per minute) increases the onset time to hypoxia-induced brain death in rats.{65778} It increases survival time and inhibits decreases in body temperature induced by hypobaric hypoxia in rats when administered at a dose of 45 mg/kg.
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