5-Aminothalidomide, CAS 191732-76-0

Formulation: A solid

Formal Name: 5-amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

Purity: ≥95%

Formula Markup: C13H11N3O4

Formula Weight: 273,2

Shelf life (days): 1460

CAS Number: 191732-76-0

Notes: 5-Aminothalidomide is a derivative of the immunomodulatory compound (±)-thalidomide (Item No. 14610). It inhibits the proliferation of EA.hy926 endothelial cells (IC50 = 200 µM).{72269} 5-Aminothalidomide is an intermediate in the synthesis of a PROTAC c-MET degrader with antiproliferative activity in c-MET-sensitive EBC-1 and Hs 746T cancer cells.{72270} It is also an intermediate in the synthesis of a thalidomide derivative that reduces clinical scores in a mouse model of experimental autoimmune encephalomyelitis (EAE).{72269}

• SKU: CAY39514-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39514-5
• Package Unit: 5 g
• Quantity Unit: STK