Product Description: Alteplase (Actilyse; Activase), a tissue plasminogen activator prepared by recombination, is a thrombolytic agent that play important roles in acute ischemic stroke, pulmonary embolism, acute myocardial infarction, and occluded catheters[1][2][3][4].
Applications: Neuroscience-Neuromodulation
Formula: N/A
References: [1]J Bastecký, et al. [Actilyse (a recombinant tissue-type plasminogen activator] in the treatment of acute myocardial infarct. Comparison of the effects of Actilyse and streptokinase]. Vnitr Lek. 1994 May;40(5):293-8./[2]Micieli G, et al. Safety and efficacy of alteplase in the treatment of acute ischemic stroke. Vasc Health Risk Manag. 2009;5(1):397-409. /[3]Orset C, et al. Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis. Stroke. 2016 May;47(5):1312-1318. /[4]Kimura S, et al. Cytotoxic effects of alteplase, a recombinant tissue plasminogen activator, on human retinal pigment epithelial cells. Jpn J Ophthalmol. 2021 Sep;65(5):731-739.
CAS Number: 105857-23-6
Molecular Weight: N/A
Research Area: Cardiovascular Disease; Cancer
Solubility: 10 mM in DMSO
Target: Others
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