AT-1, CAS 2098836-45-2

Formulation: A solid

Formal Name: (4R)-N-acetyl-3-[[6-[[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]amino]hexyl]thio]-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide

Purity: ≥98%

Formula Markup: C48H58ClN9O5S3

CAS Number: 2098836-45-2

Notes: AT-1 is a proteolysis-targeting chimera (PROTAC) that contains the bromodomain and extra terminal (BET) domain-containing protein inhibitor (+)-JQ1 (Item No. 11187) conjugated to PROTAC building block VH ligand 032 (Item No. 39982).{67805} It selectively degrades bromodomain-containing protein 4 (BRD4) over BRD3 and BRD2 in HeLa cells at 300 nM.

• SKU: CAY33265-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33265-500
• Package Unit: 500 µg
• Quantity Unit: STK