E3 Ligand-Linker Conjugate 3, CAS 1799711-24-2

Formulation: A solid

Formal Name: N-(4-aminobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-acetamide

Purity: ≥95%

Formula Markup: C19H22N4O6

Formula Weight: 402,4

Shelf life (days): 1460

CAS Number: 1799711-24-2

Notes: E3 ligand-linker conjugate 3 is a building block in the synthesis of proteolysis-targeting chimera (PROTAC) technologies containing thalidomide (Item No. 14610), which is a ligand for the E3 ubiquitin ligase cereblon.{67087,67088} It has been used in the synthesis of PROTACs for the degradation of several proteins, including anaplastic lymphoma kinase (ALK) and the bromodomain and extra terminal domain (BET) family of proteins, with anticancer activity.

• SKU: CAY36666-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36666-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK
• Application: Reinstoffe