Product Description: Elastase, Porcine pancreas (EC 3.4.21.36) is a single polypeptide chain of 240 amino acid residues, derived from pig pancreas. Elastase, Porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters[1][2][3].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C1135H1759N331O346S10
References: [1]Shotton DM, et, al. Amino-acid sequence of porcine pancreatic elastase and its homologies with other serine proteinases. Nature. 1970 Feb 28;225(5235):802-6./[2]Teshima T, et, al. A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates. J Biol Chem. 1982 May 10;257(9):5085-91./[3]Stone PJ, et, al. Induction and exacerbation of emphysema in hamsters with human neutrophil elastase inactivated reversibly by a peptide boronic acid. Am Rev Respir Dis. 1990 Jan;141(1):47-52.
CAS Number: 39445-21-1
Molecular Weight: 25898.13
Research Area: Metabolic Disease
Solubility: H2O : < 0.1 mg/mL (ultrasonic)/H2O : 50 mg/mL (ultrasonic;adjust pH to 9 with NaOH)
Target: Elastase
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