Product Description: Endo-β-N-acetylglucosaminidase F2 (Endo F2), a highly specific endoglycosidase, cleaves within the chitobiose core of asparagine-linked complex biantennary and high mannose oligosaccharides from glycoproteins and glycopeptides. Endo F2 cleaves biantennary glycans at a rate approximately 20 times greater than high mannose glycans. The activity of Endo F2 is identical on biantennary structures with and without core fucosylation. Endo F2 is not active on hybrid or tri- and tetra-antennary oligosaccharides[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: N/A
References: [1]R B Trimble, et al. Identification of distinct endoglycosidase (endo) activities in Flavobacterium meningosepticum: endo F1, endo F2, and endo F3. Endo F1 and endo H hydrolyze only high mannose and hybrid glycans. J Biol Chem. 1991 Jan 25;266(3):1646-51.
CAS Number: 37278-88-9
Molecular Weight: N/A
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Others
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