Product Description: Isocitrate dehydrogenase, Porcine heart (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P)+ to NAD(P)H, it plays important roles in cellular metabolism[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: N/A
References: [1]Reitman ZJ, Yan H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst. 2010 Jul 7;102(13):932-41.
CAS Number: 9028-48-2
Molecular Weight: N/A
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Isocitrate Dehydrogenase (IDH)