N-Acetylgalactosaminyltransferase 4

Product Description: N-Acetylgalactosaminyltransferase 4 (GALNT4) is a glycosyltransferase capable of inhibiting the activation of ASK1. By directly binding to ASK1, N-Acetylgalactosaminyltransferase 4 suppresses its N-terminal dimerization and subsequent phosphorylation, leading to robust inactivation of downstream JNK/p38 and NF-κB signals, and thereby improving the prognosis of liver surgery[1].

Formula: N/A

References: [1]Zhou J, et al. N-acetylgalactosaminyltransferase-4 protects against hepatic ischemia/reperfusion injury by blocking apoptosis signal-regulating kinase 1 N-terminal dimerization. Hepatology. 2022;75(6):1446-1460.

Molecular Weight: N/A

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: JNK;MAP3K;NF-κB;p38 MAPK

• SKU: MEXHY-E70291-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-E70291-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK