Prorenin (human, recombinant)

Formulation: 50 mM Tris-HCl, pH 8.0, with 150 mM sodium chloride and 5% glycerol

Purity: ≥90% estimated by SDS-PAGE

Shelf life (days): 365

Notes: Prorenin is the inactive precursor of renin, which is a key enzyme in the regulation of blood pressure and electrolyte balance. In renal juxtaglomerular cells, sequential cleavage of the N-terminal 20 and 46 amino acids of preprorenin produces prorenin and active renin, respectively.{12968} Renin catalyzes the conversion of angiotensinogen to angiotensin I.{12331} Prorenin exhibits 5-10% of the proteolytic activity of renin, however, the blood circulating levels are 10 times higher.{13379,13368}

• SKU: CAY10007599
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10007599-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK