Pyruvate carboxylase, CAS 9014-19-1

Product Description: Pyruvate carboxylase is a biotin-containing enzyme that catalyzes the HCO3− and MgATP dependent carboxylation of pyruvate to form oxaloacetate. Pyruvate carboxylase plays an essential role in controlling whole-body energetics through regulation of gluconeogenesis in the liver, synthesis of fatty acids in adipocytes, and insulin secretion in pancreatic β cells[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: N/A

References: [1]Jitrapakdee S, et al. Structure, mechanism and regulation of pyruvate carboxylase. Biochem J. 2008 Aug 1;413(3):369-87./[2]Kiesel VA, et al. Pyruvate carboxylase and cancer progression. Cancer Metab. 2021 Apr 30;9(1):20.

CAS Number: 9014-19-1

Molecular Weight: N/A

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite

• SKU: MEXHY-P2989-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P2989-10
• Green Labware: No
• Package Unit: 10 units
• Quantity Unit: STK