SpCas9 D10A Nickase

Product Description: SpCas9 D10A Nickase is a mutant of the Cas9 protein. SpCas9 D10A Nickase retains the function of a cleavage domain of Cas9 nuclease and specifically cleaves the target single strand to form a nick. SpCas9 D10A Nickase reduces off-target effects[1].

Formula: N/A

References: [1]Jasper Che-Yung Chien, et al. Multiplexed bioluminescence-mediated tracking of DNA double-strand break repairs in vitro and in vivo. Nat Protoc. 2021, 16, 8.

Molecular Weight: N/A

Research Area: Others

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-E70219-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-E70219-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK