ST3 β-Gal α-2,3-Sialyltransferase 1

Product Description: ST3 β-Gal α-2,3-Sialyltransferase 1 (ST3GAL1) is a sialyltransferase whose overexpression in ovarian cancer cell lines enhances cell growth, migration, and invasion capabilities, as well as increases tumorigenicity and resistance to paclitaxel in vivo. ST3 β-Gal α-2,3-Sialyltransferase 1 catalyzes the transfer of sialic acid from cytidine monophosphate-sialic acid to galactose-containing substrates and can be utilized in studies of cancer progression and chemotherapy resistance[1].

Formula: N/A

References: [1]Wu X, et al. Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-β1-induced EMT and confers paclitaxel resistance in ovarian cancer. Cell Death Dis. 2018 Oct 30;9(11):1102.

Molecular Weight: N/A

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite

• SKU: MEXHY-E70298-20UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-E70298-20UG
• Package Unit: 20 µg
• Quantity Unit: STK