Formulation: A crystalline solid
Formal Name: L-alanyl-L-α-glutamyl-L-α-aspartyl-glycine, trifluoroacetate salt
Purity: ≥95%
Formula Markup: C14H22N4O9 • XCF3COOH
Formula Weight: 390,4
Shelf life (days): 1460
Notes: Epitalon is a synthetic tetrapeptide with anti-aging activities.{64991,46382,46383,46384} It increases the lifespan of D. melanogaster imagoes when used at concentrations ranging from 0.001 to 5% in the culture medium.{64991} Epitalon (1 μg/animal) delays age-related estrous cycle shutdown and decreases the frequency of bone marrow cell chromosomal aberrations in female mice.{46382} It decreases spontaneous mammary gland and ovarian tumor development and metastasis in aged female mice when administered at a dose of 0.1 µg/animal.{46383} Epitalon (10 µg/animal) also stimulates melatonin synthesis in the evening and restores the circadian rhythm of cortisol secretion in senescent M. mulatta monkeys.{46384}
English
Deutsch
