10074-G5, CAS 413611-93-5

c-Myc inhibitor

Product Type: Inhibitor

CAS No.: 413611-93-5

MolecularFormula: C18H12N4O3

Molecular Weight: 332,3

Source: Synthetic

Purity: >98% (TLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (40 mg/ml)

Appearance: Orange powder

PubChem CID: 2836600

Scientific Background: 10074-G5 binds to and distorts the bHLH-ZIP domain of c-Myc, thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity (1). 10074-G5 is capable of binding and sequestering the intrinsically disordered amyloid-β (Aβ) peptide in its monomeric, soluble state. Our analysis reveals that this compound interacts with Aβ and inhibits both the primary and secondary nucleation pathways in its aggregation process (2).

References: 1. Follis A.V. et al. (2008) Chem. Biol. 15: 1149. 2. Heller G.T. (2020) ScienceAdvances. 6(45): DOI: 10.1126/sciadv.abb5924.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-609-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-609-5MG
• Package Unit: 5 mg
• Quantity Unit: STK